Results of a retrospective study linked statin use to diabetes progression; specifically, a greater likelihood of insulin treatment initiation, significant hyperglycemia, acute glycemic complications, and an increased number of prescriptions for glucose-lowering medication classes, researchers explained. Findings were published in JAMA Internal Medicine.
Although guidelines recommend statin therapy for all patients with type 2 diabetes aged 40 to 75 who have low-density lipoprotein (LDL) cholesterol levels of 70 mg/dL or greater, research shows the medication classes’ use has been associated with increased insulin resistance and higher blood glucose levels, the authors said.
Statins are primarily prescribed in this population to help prevent cardiovascular diseases (CVD). However, increased insulin resistance could fuel diabetes progression and subsequently increase the risk of CVD.
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